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    Per tablet. This high cost coupled with the relatively frequent adverse side effects is cause to consider other approaches to migraine prevention. Ask your physician about beta blockers, tricyclic antidepressants, or riboflavin for migraine prevention. In clinical trials, patients taking the highest dose of Qnexa, a drug that uses this duo, lost nearly 9% more weight than those taking a placebo. But because of concerns about the potential for birth defects and heart problems, the FDA decided late last year not to approve the drug. The Food and Drug Administration (FDA) has issued a notification alerting physicians who prescribe topiramate, and their patients, to the risk of vision loss (Blindness). Acute myopia and secondary angle closure glaucoma, in a small subset of patients who take topiramate regularly, may cause transient (Reversible), or permanent, loss of vision. The symptoms, which typically begin in the first month of use, include blurred vision and eye pain. If addressed early in its course, discontinuation of topiramate, along with other measures deemed prudent by the prescribing physician and/or ophthalmologist, may halt the progression of the ocular damage, and may reverse the visual impairment. Patients who take topiramate and who feel pain in or around their eyes, or notice a loss of vision, visual acuity, or blurred vision, are advised to seek consultation with their physician as soon as reasonably possible. According to the FDA: "In more than 825,000 patients.As of August 17, 2001 there have been 23 reported cases: 22 In adults and 1 in pediatric patients. It is generally recognized that postmarketing data are subject to substantial under-reporting." Stephen King. John Mellencamp. T Bone Burnett. Three instantly recognizable names. Three iconic artists with enormous fan bases and lengthy lists of professional accomplishments. And, taken together,. French JA, et al. (2004). Efficacy and tolerability of the new antiepileptic drugs I: Treatment of new onset epilepsy. Report of the Therapeutics and Technology Assessment Subcommittee and Quality Standards Subcommittee of the American Academy of Neurology and the American Epilepsy Society. Neurology, 62(8): 1252-1260.
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